Samuel B. Pegram, MD, Principal Investigator and founder of the Rheumatic Disease Clinical Research Center, has practiced Rheumatology in Southeast Houston for over two decades. Dr. Pegram and RDCRC have built a reputation for quality clinical research while conducting various clinical trials for industry leading pharmaceutical companies and clinical research organizations.

Our team is built on years of experience and professionalism; experienced Sub-Investigators, IP Pharmacy staff, and CCRP certified Study Coordinators. RDCRC performs Phase II through IV clinical trials in Rheumatology. Trials in therapeutic areas include treatments of rheumatic, autoimmune and musculoskeletal diseases.

Houston Rheumatology Research

For Our Sponsors

  • Private consultation and exam rooms
  • Secured and climate controlled investigational product areas
  • Temperature monitored refrigeration and freezer
  • Laboratory Services
  • Standard operation procedures
  • CCRP certified research staff
  • A dedicated full-time and backup coordinator assigned to each study
  • Continuous Principal Investigator and staff training through study duration
  • IATA certified staff
  • DEA licenses for scheduled drugs
  • Scheduled equipment inspections and calibration
  • Record retention to U.S. and international standards
  • On-Site long–term storage of records
  • Central IRB
  • Dedicated monitoring space
  • Extensive EDC, IWRS, and ePRO experience

For Our Patients

  • Outpatient consultations; medical history and medical records review
  • Outpatient specialty care for patients with chronic rheumatic and autoimmune diseases
  • Diagnostic bone and joint MRI scanning, X-ray, bone density scanning
  • On-site ECG
  • Therapeutic intra-articular and soft tissue injections and aspirations
  • Education on rheumatologic diseases and treatments
  • Ultrasound guided diagnostic and therapeutic intra-articular injections
  • Intravenous biologic therapy for rheumatic disease and Lupus


Learn about the latest research and treatments available.